Positive and negative allosteric modulation of GluK2 kainate receptors by BPAM344 and antiepileptic perampanel

Kainate receptors (KARs) are a subtype of ionotropic glutamate receptors that control synaptic transmission in the central nervous system and are implicated in neurological, psychiatric, and neurodevelopmental disorders. Understanding the regulation of KAR function by small molecules is essential fo...

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Detalles Bibliográficos
Autores principales: Gangwar, Shanti Pal, Yen, Laura Y., Yelshanskaya, Maria V., Sobolevsky, Alexander I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440371/
https://www.ncbi.nlm.nih.gov/pubmed/36857176
http://dx.doi.org/10.1016/j.celrep.2023.112124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440371/
https://www.ncbi.nlm.nih.gov/pubmed/36857176
http://dx.doi.org/10.1016/j.celrep.2023.112124

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