Early transcriptome changes associated with western diet induced NASH in Ldlr(−/−) mice points to activation of hepatic macrophages and an acute phase response

BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a global health problem. Identifying early gene indicators contributing to the onset and progression of NAFLD has the potential to develop novel targets for early therapeutic intervention. We report on the early and late transcriptomic signatur...

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Detalles Bibliográficos
Autores principales: Padiadpu, Jyothi, Spooner, Melinda H., Li, Zhipeng, Newman, Nolan, Löhr, Christiane V., Apperson, K. Denise, Dzutsev, Amiran, Trinchieri, Giorgio, Shulzhenko, Natalia, Morgun, Andrey, Jump, Donald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440380/
https://www.ncbi.nlm.nih.gov/pubmed/37609485
http://dx.doi.org/10.3389/fnut.2023.1147602

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440380/
https://www.ncbi.nlm.nih.gov/pubmed/37609485
http://dx.doi.org/10.3389/fnut.2023.1147602

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