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Tacrolimus/methotrexate vs tacrolimus/reduced-dose methotrexate/mycophenolate for graft-versus-host disease prevention

Tacrolimus (Tac)/methotrexate (MTX) is standard graft-versus-host disease (GVHD) prophylaxis; however, is associated with several toxicities. Tac, reduced-dose MTX (mini-MTX), and mycophenolate mofetil (MMF) have been used but never compared with standard MTX. We performed a randomized trial compari...

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Detalles Bibliográficos
Autores principales: Hamilton, Betty K., Rybicki, Lisa A., Li, Hong, Lucas, Taylor, Corrigan, Donna, Kalaycio, Matt, Sobecks, Ronald, Hanna, Rabi, Rotz, Seth J., Dean, Robert M., Gerds, Aaron T., Jagadeesh, Deepa, Brunstein, Claudio, Sauter, Craig S., Copelan, Edward A., Majhail, Navneet S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440463/
https://www.ncbi.nlm.nih.gov/pubmed/37352262
http://dx.doi.org/10.1182/bloodadvances.2023010310