Some aspects of the life of SARS-CoV-2 ORF3a protein in mammalian cells

The accessory protein ORF3a, from SARS-CoV-2, plays a critical role in viral infection and pathogenesis. Here, we characterized ORF3a assembly, ion channel activity, subcellular localization, and interactome. At the plasma membrane, ORF3a exists mostly as monomers and dimers, which do not alter the...

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Detalles Bibliográficos
Autores principales: Jiao, Song, Miranda, Pablo, Li, Yan, Maric, Dragan, Holmgren, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440475/
https://www.ncbi.nlm.nih.gov/pubmed/37609425
http://dx.doi.org/10.1016/j.heliyon.2023.e18754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440475/
https://www.ncbi.nlm.nih.gov/pubmed/37609425
http://dx.doi.org/10.1016/j.heliyon.2023.e18754

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