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Some aspects of the life of SARS-CoV-2 ORF3a protein in mammalian cells
The accessory protein ORF3a, from SARS-CoV-2, plays a critical role in viral infection and pathogenesis. Here, we characterized ORF3a assembly, ion channel activity, subcellular localization, and interactome. At the plasma membrane, ORF3a exists mostly as monomers and dimers, which do not alter the...
Autores principales: | Jiao, Song, Miranda, Pablo, Li, Yan, Maric, Dragan, Holmgren, Miguel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440475/ https://www.ncbi.nlm.nih.gov/pubmed/37609425 http://dx.doi.org/10.1016/j.heliyon.2023.e18754 |
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