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Survival in sporadic ALS is associated with lower p62 burden in the spinal cord

The autophagy marker p62 appears as a consistent component of pathological aggregates in amyotrophic lateral sclerosis (ALS) and its modulation to facilitate protein degradation has been proposed as a potential therapeutic target. Importantly, recent studies have implicated diffuse phosphorylated TD...

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Detalles Bibliográficos
Autores principales: Pinkerton, Monica, Lourenco, Guinevere, Pacheco, Maria Torres, Halliday, Glenda M, Kiernan, Matthew C, Tan, Rachel H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440721/
https://www.ncbi.nlm.nih.gov/pubmed/37414530
http://dx.doi.org/10.1093/jnen/nlad051