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The Growth Hormone Deficiency (GHD) Reversal Trial: effect on final height of discontinuation versus continuation of growth hormone treatment in pubertal children with isolated GHD—a non-inferiority Randomised Controlled Trial (RCT)

BACKGROUND: Growth hormone deficiency (GHD) is the commonest endocrine cause of short stature and may occur in isolation (I-GHD) or combined with other pituitary hormone deficiencies. Around 500 children are diagnosed with GHD every year in the UK, of whom 75% have I-GHD. Growth hormone (GH) therapy...

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Detalles Bibliográficos
Autores principales: Brettell, Elizabeth, Högler, Wolfgang, Woolley, Rebecca, Cummins, Carole, Mathers, Jonathan, Oppong, Raymond, Roy, Laura, Khan, Adam, Hunt, Charmaine, Dattani, Mehul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440873/
https://www.ncbi.nlm.nih.gov/pubmed/37605233
http://dx.doi.org/10.1186/s13063-023-07562-z