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The Growth Hormone Deficiency (GHD) Reversal Trial: effect on final height of discontinuation versus continuation of growth hormone treatment in pubertal children with isolated GHD—a non-inferiority Randomised Controlled Trial (RCT)
BACKGROUND: Growth hormone deficiency (GHD) is the commonest endocrine cause of short stature and may occur in isolation (I-GHD) or combined with other pituitary hormone deficiencies. Around 500 children are diagnosed with GHD every year in the UK, of whom 75% have I-GHD. Growth hormone (GH) therapy...
Autores principales: | Brettell, Elizabeth, Högler, Wolfgang, Woolley, Rebecca, Cummins, Carole, Mathers, Jonathan, Oppong, Raymond, Roy, Laura, Khan, Adam, Hunt, Charmaine, Dattani, Mehul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440873/ https://www.ncbi.nlm.nih.gov/pubmed/37605233 http://dx.doi.org/10.1186/s13063-023-07562-z |
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