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Comparison of Bayesian Networks, G-estimation and linear models to estimate causal treatment effects in aggregated N-of-1 trials with carry-over effects

BACKGROUND: The aggregation of a series of N-of-1 trials presents an innovative and efficient study design, as an alternative to traditional randomized clinical trials. Challenges for the statistical analysis arise when there is carry-over or complex dependencies of the treatment effect of interest....

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Detalles Bibliográficos
Autores principales: Gärtner, Thomas, Schneider, Juliana, Arnrich, Bert, Konigorski, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440905/
https://www.ncbi.nlm.nih.gov/pubmed/37605171
http://dx.doi.org/10.1186/s12874-023-02012-5