Differential effects of PGAM5 knockout on high fat high fructose diet and methionine choline-deficient diet induced non-alcoholic steatohepatitis (NASH) in mice

BACKGROUND: Phosphoglycerate mutase 5 (PGAM5), a phosphatase involved in mitochondrial homeostasis, is reported to be closely related to the metabolic stress induced by high-fat diet (HFD) or cold. In this study, we aimed to investigate the effects of PGAM5 on hepatic steatosis, inflammation and fib...

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Detalles Bibliográficos
Autores principales: Li, Li, Guo, Chengcheng, Yu, Yue, Tie, Lu, Lu, Guotao, Liu, Feng, Han, Xueyao, Ji, Linong, Zou, Xiantong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440915/
https://www.ncbi.nlm.nih.gov/pubmed/37605246
http://dx.doi.org/10.1186/s13578-023-01095-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440915/
https://www.ncbi.nlm.nih.gov/pubmed/37605246
http://dx.doi.org/10.1186/s13578-023-01095-3

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