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Differential effects of PGAM5 knockout on high fat high fructose diet and methionine choline-deficient diet induced non-alcoholic steatohepatitis (NASH) in mice
BACKGROUND: Phosphoglycerate mutase 5 (PGAM5), a phosphatase involved in mitochondrial homeostasis, is reported to be closely related to the metabolic stress induced by high-fat diet (HFD) or cold. In this study, we aimed to investigate the effects of PGAM5 on hepatic steatosis, inflammation and fib...
Autores principales: | Li, Li, Guo, Chengcheng, Yu, Yue, Tie, Lu, Lu, Guotao, Liu, Feng, Han, Xueyao, Ji, Linong, Zou, Xiantong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440915/ https://www.ncbi.nlm.nih.gov/pubmed/37605246 http://dx.doi.org/10.1186/s13578-023-01095-3 |
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