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Current approaches to develop “off-the-shelf” chimeric antigen receptor (CAR)-T cells for cancer treatment: a systematic review

Chimeric antigen receptor (CAR)-T cell therapy is one of the most promising advances in cancer treatment. It is based on genetically modified T cells to express a CAR, which enables the recognition of the specific tumour antigen of interest. To date, CAR-T cell therapies approved for commercialisati...

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Detalles Bibliográficos
Autores principales: Aparicio, Cristina, Acebal, Carlos, González-Vallinas, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440917/
https://www.ncbi.nlm.nih.gov/pubmed/37605218
http://dx.doi.org/10.1186/s40164-023-00435-w