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In vivo deglycosylation of recombinant glycoproteins in tobacco BY‐2 cells

Production of recombinant pharmaceutical glycoproteins has been carried out in multiple expression systems. However, N‐glycosylation, which increases heterogeneity and raises safety concerns due to the presence of non‐human residues, is usually not controlled. The presence and composition of N‐glyca...

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Detalles Bibliográficos
Autores principales: Herman, Xavier, Far, Johann, Peeters, Marie, Quinton, Loïc, Chaumont, François, Navarre, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10440984/
https://www.ncbi.nlm.nih.gov/pubmed/37266972
http://dx.doi.org/10.1111/pbi.14074