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KGML-xDTD: a knowledge graph–based machine learning framework for drug treatment prediction and mechanism description

BACKGROUND: Computational drug repurposing is a cost- and time-efficient approach that aims to identify new therapeutic targets or diseases (indications) of existing drugs/compounds. It is especially critical for emerging and/or orphan diseases due to its cheaper investment and shorter research cycl...

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Detalles Bibliográficos
Autores principales: Ma, Chunyu, Zhou, Zhihan, Liu, Han, Koslicki, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441000/
https://www.ncbi.nlm.nih.gov/pubmed/37602759
http://dx.doi.org/10.1093/gigascience/giad057