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Transforming the untransformable with knockout minicircles

Gene inactivation studies are critical in pathogenic bacteria, where insights into species biology can guide the development of vaccines and treatments. Allelic exchange via homologous recombination is a generic method of targeted gene editing in bacteria. However, generally applicable protocols are...

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Detalles Bibliográficos
Autores principales: Rudenko, Oleksandra, Baseggio, Laura, McGuigan, Fynn, Barnes, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441182/
https://www.ncbi.nlm.nih.gov/pubmed/37642481
http://dx.doi.org/10.1002/mbo3.1374