Pathogenic soluble tau peptide disrupts endothelial calcium signaling and vasodilation in the brain microvasculature

The accumulation of the microtubule-associated tau protein in and around blood vessels contributes to brain microvascular dysfunction through mechanisms that are incompletely understood. Delivery of nutrients to active neurons in the brain relies on capillary inositol 1,4,5-triphosphate receptor (IP...

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Detalles Bibliográficos
Autores principales: Freeman, Kalev, Sackheim, Adrian M, Mughal, Amreen, Koide, Masayo, Bonson, Grace, Ebner, Grace, Hennig, Grant, Lockette, Warren, Nelson, Mark T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441279/
https://www.ncbi.nlm.nih.gov/pubmed/37609200
http://dx.doi.org/10.1101/2023.08.08.552492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441279/
https://www.ncbi.nlm.nih.gov/pubmed/37609200
http://dx.doi.org/10.1101/2023.08.08.552492

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