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Pathogenic soluble tau peptide disrupts endothelial calcium signaling and vasodilation in the brain microvasculature
The accumulation of the microtubule-associated tau protein in and around blood vessels contributes to brain microvascular dysfunction through mechanisms that are incompletely understood. Delivery of nutrients to active neurons in the brain relies on capillary inositol 1,4,5-triphosphate receptor (IP...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441279/ https://www.ncbi.nlm.nih.gov/pubmed/37609200 http://dx.doi.org/10.1101/2023.08.08.552492 |