PHOSPHORYLATION-DEPENDENT ASSOCIATION OF WRN WITH RPA IS REQUIRED FOR RECOVERY OF REPLICATION FORKS STALLED AT SECONDARY DNA STRUCTURES

The WRN protein mutated in the hereditary premature aging disorder Werner syndrome plays a vital role in handling, processing, and restoring perturbed replication forks. One of its most abundant partners, Replication Protein A (RPA), has been shown to robustly enhance WRN helicase activity in specif...

Descripción completa

Detalles Bibliográficos
Autores principales: Noto, Alessandro, Valenzisi, Pasquale, Fratini, Federica, Kulikowicz, Tomasz, Sommers, Joshua A., Di Feo, Flavia, Palermo, Valentina, Semproni, Maurizio, Crescenzi, Marco, Brosh, Robert M., Franchitto, Annapaola, Pichierri, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441285/
https://www.ncbi.nlm.nih.gov/pubmed/37609214
http://dx.doi.org/10.1101/2023.08.08.552428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441285/
https://www.ncbi.nlm.nih.gov/pubmed/37609214
http://dx.doi.org/10.1101/2023.08.08.552428

Ejemplares similares