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The actin binding protein profilin 1 is critical for mitochondria function

Profilin 1 (PFN1) is an actin binding protein that is vital for the polymerization of monomeric actin into filaments. Here we screened knockout cells for novel functions of PFN1 and discovered that mitophagy, a type of selective autophagy that removes defective or damaged mitochondria from the cell,...

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Detalles Bibliográficos
Autores principales: Read, Tracy-Ann, Cisterna, Bruno A., Skruber, Kristen, Ahmadieh, Samah, Lindamood, Halli L., Vitriol, Josefine A., Shi, Yang, Lefebvre, Austin E.Y.T., Black, Joseph B., Butler, Mitchell T., Bear, James E., Cherezova, Alena, Ilatovskaya, Daria V., Weintraub, Neil L., Vitriol, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441311/
https://www.ncbi.nlm.nih.gov/pubmed/37609280
http://dx.doi.org/10.1101/2023.08.07.552354