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The actin binding protein profilin 1 is critical for mitochondria function
Profilin 1 (PFN1) is an actin binding protein that is vital for the polymerization of monomeric actin into filaments. Here we screened knockout cells for novel functions of PFN1 and discovered that mitophagy, a type of selective autophagy that removes defective or damaged mitochondria from the cell,...
Autores principales: | Read, Tracy-Ann, Cisterna, Bruno A., Skruber, Kristen, Ahmadieh, Samah, Lindamood, Halli L., Vitriol, Josefine A., Shi, Yang, Lefebvre, Austin E.Y.T., Black, Joseph B., Butler, Mitchell T., Bear, James E., Cherezova, Alena, Ilatovskaya, Daria V., Weintraub, Neil L., Vitriol, Eric A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441311/ https://www.ncbi.nlm.nih.gov/pubmed/37609280 http://dx.doi.org/10.1101/2023.08.07.552354 |
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