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Force-induced site-specific enzymatic cleavage probes reveal that serial mechanical engagement boosts T cell activation
The surface of T cells is studded with T cell receptors (TCRs) that are used to scan target cells to identify peptide-major histocompatibility complexes (pMHCs) signatures of viral infection or cancerous mutation. It is now established that the TCR-pMHC complex is highly transient and experiences me...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441320/ https://www.ncbi.nlm.nih.gov/pubmed/37609308 http://dx.doi.org/10.1101/2023.08.07.552310 |