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The sterol C-24 methyltransferase encoding gene, erg6, is essential for viability of Aspergillus species

Ergosterol is a critical component of fungal plasma membranes. Although many currently available antifungal compounds target the ergosterol biosynthesis pathway for antifungal effect, current knowledge regarding ergosterol synthesis remains incomplete for filamentous fungal pathogens like Aspergillu...

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Detalles Bibliográficos
Autores principales: Xie, Jinhong, Rybak, Jeffrey M., Martin-Vicente, Adela, Guruceaga, Xabier, Thorn, Harrison I., Nywening, Ashley V., Ge, Wenbo, Parker, Josie E., Kelly, Steven L., Rogers, P. David, Fortwendel, Jarrod R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441335/
https://www.ncbi.nlm.nih.gov/pubmed/37609350
http://dx.doi.org/10.1101/2023.08.08.552489