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An Aurora kinase A-BOD1L1-PP2A B56 Axis promotes chromosome segregation fidelity
Cancer cells are often aneuploid and frequently display elevated rates of chromosome mis-segregation in a phenomenon called chromosomal instability (CIN). CIN is commonly caused by hyperstable kinetochore-microtubule (K-MT) attachments that reduces the efficiency of correction of erroneous K-MT atta...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441337/ https://www.ncbi.nlm.nih.gov/pubmed/37609141 http://dx.doi.org/10.1101/2023.08.06.552174 |