The RIDD activity of C. elegans IRE1 modifies neuroendocrine signaling in anticipation of environment stress to ensure survival

Xbp1 splicing and regulated IRE1-dependent RNA decay (RIDD) are two RNase activities of the ER stress sensor IRE1. While Xbp1 splicing has important roles in stress responses and animal physiology, the physiological role(s) of RIDD remain enigmatic. Genetic evidence in C. elegans connects XBP1-indep...

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Detalles Bibliográficos
Autores principales: Mingjie, Ying, Yair, Argon, Tali, Gidalevitz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441387/
https://www.ncbi.nlm.nih.gov/pubmed/37609168
http://dx.doi.org/10.1101/2023.08.10.552841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441387/
https://www.ncbi.nlm.nih.gov/pubmed/37609168
http://dx.doi.org/10.1101/2023.08.10.552841

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