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Brain Specific Estrogen Ameliorates Cognitive Effects of Surgical Menopause in Mice

Menopause is a major endocrinological shift that leads to an increased vulnerability to the risk factors for cognitive impairment and dementia. This is thought to be due to the loss of circulating estrogens, which exert many potent neuroprotective effects in the brain. Systemic replacement of estrog...

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Detalles Bibliográficos
Autores principales: Salinero, Abigail E., Abi-Ghanem, Charly, Venkataganesh, Harini, Sura, Avi, Smith, Rachel M., Thrasher, Christina A., Kelly, Richard D., Hatcher, Katherine M., NyBlom, Vanessa, Shamlian, Victoria, Kyaw, Nyi-Rein, Belanger, Kasey M., Gannon, Olivia J., Stephens, Shannon B.Z., Zuloaga, Damian G., Zuloaga, Kristen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441397/
https://www.ncbi.nlm.nih.gov/pubmed/37609180
http://dx.doi.org/10.1101/2023.08.09.552687