An adult clock component links circadian rhythms to pancreatic β-cell maturation

How ubiquitous circadian clocks orchestrate tissue-specific outputs is not well understood. Pancreatic β cell-autonomous clocks attune insulin secretion to daily energy cycles, and desynchrony from genetic or behavioral disruptions raises type 2 diabetes risk. We show that the transcription factor D...

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Detalles Bibliográficos
Autores principales: Montalvo, Ana P., Gruskin, Zoe L., Leduc, Andrew, Liu, Mai, Gao, Zihan, Ahn, June H., Straubhaar, Juerg R., Slavov, Nikolai, Alvarez-Dominguez, Juan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441398/
https://www.ncbi.nlm.nih.gov/pubmed/37609178
http://dx.doi.org/10.1101/2023.08.11.552890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441398/
https://www.ncbi.nlm.nih.gov/pubmed/37609178
http://dx.doi.org/10.1101/2023.08.11.552890

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