SUMOylation of the m6A reader YTHDF2 by PIAS1 promotes viral RNA decay to restrict EBV replication

YTHDF2 is a member of the YTH protein family that binds to N6-methyladenosine (m6A)-modified RNA, regulating RNA stability and restricting viral replication, including Epstein-Barr virus (EBV). PIAS1 is an E3 SUMO ligase known as an EBV restriction factor, but its role in YTHDF2 SUMOylation remains...

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Detalles Bibliográficos
Autores principales: Sugiokto, Febri Gunawan, Saiada, Farjana, Zhang, Kun, Li, Renfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441406/
https://www.ncbi.nlm.nih.gov/pubmed/37609256
http://dx.doi.org/10.1101/2023.08.08.552509

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441406/
https://www.ncbi.nlm.nih.gov/pubmed/37609256
http://dx.doi.org/10.1101/2023.08.08.552509

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