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Unleashing the Power of NR4A1 Degradation as a Novel Strategy for Cancer Immunotherapy

An effective cancer therapy requires both killing cancer cells and targeting tumor-promoting pathways or cell populations within the tumor microenvironment (TME). We purposely search for molecules that are critical for multiple tumor-promoting cell types and identified nuclear receptor subfamily 4 g...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Xiao, Yufeng, Luo, Yuewan, Master, Rohan P, Mo, Jiao, Kim, Myung-Chul, Liu, Yi, Patel, Urvi M, Li, Xiangming, Shaffer, Donald, Guertin, Kevin R, Moser, Emily, Smalley, Keiran S., Zhou, Daohong, Zheng, Guangrong, Zhang, Weizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441411/
https://www.ncbi.nlm.nih.gov/pubmed/37609171
http://dx.doi.org/10.1101/2023.08.09.552650