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Microcystin-RR is a biliary toxin selective for neonatal cholangiocytes

BACKGROUND AND AIMS: Biliary atresia is a fibrosing cholangiopathy affecting neonates that is thought to be caused by a prenatal environmental insult to the bile duct. Biliatresone, a plant toxin with an α-methylene ketone group, was previously implicated in toxin-induced biliary atresia in Australi...

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Detalles Bibliográficos
Autores principales: Gupta, Kapish, Chen, Dongning, Wells, Rebecca G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441435/
https://www.ncbi.nlm.nih.gov/pubmed/37609158
http://dx.doi.org/10.1101/2023.08.09.552661