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Topical application of calcitonin gene-related peptide as a regenerative, antifibrotic, and immunomodulatory therapy for corneal injury

Calcitonin gene-related peptide (CGRP) is a multifunctional neuropeptide abundantly expressed by corneal nerves. Using a murine model of corneal mechanical injury, we found CGRP levels in the cornea to be significantly reduced after injury. Topical application of CGRP as an eye drop three times dail...

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Detalles Bibliográficos
Autores principales: Zidan, Asmaa A., Zhu, Shuyan, Elbasiony, Elsayed, Najafi, Sheyda, Lin, Zhirong, Singh, Rohan Bir, Naderi, Amirreza, Yin, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441448/
https://www.ncbi.nlm.nih.gov/pubmed/37609298
http://dx.doi.org/10.21203/rs.3.rs-3204385/v1