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Topical application of calcitonin gene-related peptide as a regenerative, antifibrotic, and immunomodulatory therapy for corneal injury
Calcitonin gene-related peptide (CGRP) is a multifunctional neuropeptide abundantly expressed by corneal nerves. Using a murine model of corneal mechanical injury, we found CGRP levels in the cornea to be significantly reduced after injury. Topical application of CGRP as an eye drop three times dail...
Autores principales: | Zidan, Asmaa A., Zhu, Shuyan, Elbasiony, Elsayed, Najafi, Sheyda, Lin, Zhirong, Singh, Rohan Bir, Naderi, Amirreza, Yin, Jia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441448/ https://www.ncbi.nlm.nih.gov/pubmed/37609298 http://dx.doi.org/10.21203/rs.3.rs-3204385/v1 |
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