Immortalized Mesenchymal Stromal Cells Overexpressing Alpha-1 Antitrypsin Protect Acinar Cells from Apoptotic and Ferroptotic Cell Death

Chronic pancreatitis (CP) is a progressive inflammatory disorder that impairs endocrine and exocrine function. Our previous work suggests that mesenchymal stem/stromal cells (MSCs) and MSCs overexpressing alpha-1 antitrypsin (AAT-MSCs) could be therapeutic tools for CP treatment in mouse models. How...

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Detalles Bibliográficos
Autores principales: Shoeibi, Sara, Green, Erica, Wei, Hua, Gou, Wenyu, Strange, Charlie, Wang, Hongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441457/
https://www.ncbi.nlm.nih.gov/pubmed/37609340
http://dx.doi.org/10.21203/rs.3.rs-2961444/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441457/
https://www.ncbi.nlm.nih.gov/pubmed/37609340
http://dx.doi.org/10.21203/rs.3.rs-2961444/v1

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