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Single-cell RNA sequencing reveals the cellular and molecular heterogeneity of treatment-naïve primary osteosarcoma in dogs

Osteosarcoma (OS) is a heterogeneous, aggressive malignancy of the bone that disproportionally affects children and adolescents. Therapeutic interventions for OS are limited, which is in part due to the complex tumor microenvironment (TME) that has proven to be refractory to immunotherapies. Thus, t...

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Detalles Bibliográficos
Autores principales: Ammons, Dylan, Hopkins, Leone, Cronise, Kathryn, Kurihara, Jade, Regan, Daniel, Dow, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441479/
https://www.ncbi.nlm.nih.gov/pubmed/37609233
http://dx.doi.org/10.21203/rs.3.rs-3232360/v1