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Single-cell RNA sequencing reveals the cellular and molecular heterogeneity of treatment-naïve primary osteosarcoma in dogs
Osteosarcoma (OS) is a heterogeneous, aggressive malignancy of the bone that disproportionally affects children and adolescents. Therapeutic interventions for OS are limited, which is in part due to the complex tumor microenvironment (TME) that has proven to be refractory to immunotherapies. Thus, t...
Autores principales: | Ammons, Dylan, Hopkins, Leone, Cronise, Kathryn, Kurihara, Jade, Regan, Daniel, Dow, Steven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441479/ https://www.ncbi.nlm.nih.gov/pubmed/37609233 http://dx.doi.org/10.21203/rs.3.rs-3232360/v1 |
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