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Machine Learning Ensemble Directed Engineering of Genetically Encoded Fluorescent Calcium Indicators

In this study, we focused on the transformative potential of machine learning in the engineering of genetically encoded fluorescent indicators (GEFIs), protein-based sensing tools that are critical for real-time monitoring of biological activity. GEFIs are complex proteins with multiple dynamic stat...

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Detalles Bibliográficos
Autores principales: Wait, Sarah J., Rappleye, Michael, Lee, Justin Daho, Goy, Marc Exposit, Smith, Netta, Berndt, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441480/
https://www.ncbi.nlm.nih.gov/pubmed/37609342
http://dx.doi.org/10.21203/rs.3.rs-3146778/v1