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The ABCD-GENE score influences vascular event rates in both users of clopidogrel and aspirin, as well as non-users of either drug in a population-based cohort study

BACKGROUND AND OBJECTIVES: Clopidogrel is an antiplatelet used in both primary and secondary prevention of cardiovascular diseases. It is a prodrug, requiring CYP2C19 for its metabolism to the active metabolite. The ABCD-GENE score, combining clinical attributes (age, body mass index, chronic kidney...

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Detalles Bibliográficos
Autores principales: Narasimhalu, Kaavya, Mayerhofer, Ernst, Parodi, Livia, Georgakis, Marios K, De Silva, Deidre Anne, Rosand, Jonathan, Anderson, Christopher D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441502/
https://www.ncbi.nlm.nih.gov/pubmed/37609315
http://dx.doi.org/10.1101/2023.08.06.23293732