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The ABCD-GENE score influences vascular event rates in both users of clopidogrel and aspirin, as well as non-users of either drug in a population-based cohort study
BACKGROUND AND OBJECTIVES: Clopidogrel is an antiplatelet used in both primary and secondary prevention of cardiovascular diseases. It is a prodrug, requiring CYP2C19 for its metabolism to the active metabolite. The ABCD-GENE score, combining clinical attributes (age, body mass index, chronic kidney...
Autores principales: | Narasimhalu, Kaavya, Mayerhofer, Ernst, Parodi, Livia, Georgakis, Marios K, De Silva, Deidre Anne, Rosand, Jonathan, Anderson, Christopher D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441502/ https://www.ncbi.nlm.nih.gov/pubmed/37609315 http://dx.doi.org/10.1101/2023.08.06.23293732 |
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