Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria

Malaria is caused by Plasmodium parasites and was responsible for over 247 million infections and 619,000 deaths in 2021. Radiation-attenuated sporozoite (RAS) vaccines can completely prevent blood stage infection by inducing protective liver-resident memory CD8(+) T cells. Such T cells can be induc...

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Detalles Bibliográficos
Autores principales: Watson, Felicia N, Shears, Melanie J, Kalata, Anya C, Duncombe, Caroline J, Seilie, A Mariko, Chavtur, Chris, Conrad, Ethan, Talavera, Irene Cruz, Raappana, Andrew, Sather, D Noah, Chakravarty, Sumana, Sim, B Kim Lee, Hoffman, Stephen L, Tsuji, Moriya, Murphy, Sean C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441511/
https://www.ncbi.nlm.nih.gov/pubmed/37609210
http://dx.doi.org/10.21203/rs.3.rs-3243319/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441511/
https://www.ncbi.nlm.nih.gov/pubmed/37609210
http://dx.doi.org/10.21203/rs.3.rs-3243319/v1

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