ABCB1 and ABCG2 Regulation at the Blood-Brain Barrier: Potential New Targets to Improve Brain Drug Delivery

The drug efflux transporters ABCB1 and ABCG2 at the blood-brain barrier limit the delivery of drugs into the brain. Strategies to overcome ABCB1/ABCG2 have been largely unsuccessful, which poses a tremendous clinical problem to successfully treat central nervous system (CNS) diseases. Understanding...

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Detalles Bibliográficos
Autores principales: Schulz, Julia A., Hartz, Anika M.S., Bauer, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441638/
https://www.ncbi.nlm.nih.gov/pubmed/36973040
http://dx.doi.org/10.1124/pharmrev.120.000025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441638/
https://www.ncbi.nlm.nih.gov/pubmed/36973040
http://dx.doi.org/10.1124/pharmrev.120.000025

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