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Soluble CX3CL1-expressing retinal pigment epithelium cells protect rod photoreceptors in a mouse model of retinitis pigmentosa

BACKGROUND: Retinitis pigmentosa (RP) is an inherited retinal disease that results in photoreceptor degeneration, leading to severe vision loss or blindness. Due to its genetic heterogeneity, developing a new gene therapy to correct every genetic mutation contributing to its progression is infeasibl...

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Detalles Bibliográficos
Autores principales: Jong, Eric D., Hacibekiroglu, Sabiha, Guo, Lily, Sawula, Evan, Li, Biao, Li, Chengjin, Ho, Margaret T., Shoichet, Molly S., Wallace, Valerie A., Nagy, Andras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441732/
https://www.ncbi.nlm.nih.gov/pubmed/37605279
http://dx.doi.org/10.1186/s13287-023-03434-0