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Soluble CX3CL1-expressing retinal pigment epithelium cells protect rod photoreceptors in a mouse model of retinitis pigmentosa
BACKGROUND: Retinitis pigmentosa (RP) is an inherited retinal disease that results in photoreceptor degeneration, leading to severe vision loss or blindness. Due to its genetic heterogeneity, developing a new gene therapy to correct every genetic mutation contributing to its progression is infeasibl...
Autores principales: | Jong, Eric D., Hacibekiroglu, Sabiha, Guo, Lily, Sawula, Evan, Li, Biao, Li, Chengjin, Ho, Margaret T., Shoichet, Molly S., Wallace, Valerie A., Nagy, Andras |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441732/ https://www.ncbi.nlm.nih.gov/pubmed/37605279 http://dx.doi.org/10.1186/s13287-023-03434-0 |
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