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Knockdown of long noncoding RNA SAN rejuvenates aged adipose-derived stem cells via miR-143-3p/ADD3 axis

BACKGROUND: Senescent adipose-derived stem cells (ASCs) exhibit reduced therapeutic efficacy during wound healing. Transcriptional regulation factors including long noncoding RNAs (lncRNAs) reportedly have essential roles in stem cell aging. However, the mechanisms of which lncRNAs influence mesench...

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Detalles Bibliográficos
Autores principales: Xiong, Hewei, Ren, Sen, Chen, Jing, Yang, Xiaofan, Liu, Yutian, Xu, Zhao, Guo, Jiahe, Jiang, Tao, Yuan, Meng, Liu, Yang, Zhang, Guolei, Li, Wenqing, Machens, Hans-Günther, Chen, Zhenbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441736/
https://www.ncbi.nlm.nih.gov/pubmed/37605290
http://dx.doi.org/10.1186/s13287-023-03441-1