TDP-43-regulated cryptic RNAs accumulate in Alzheimer’s disease brains

BACKGROUND: Inclusions of TAR DNA-binding protein 43 kDa (TDP-43) has been designated limbic-predominant, age-related TDP-43 encephalopathy (LATE), with or without co-occurrence of Alzheimer’s disease (AD). Approximately, 30–70% AD cases present TDP-43 proteinopathy (AD-TDP), and a greater disease s...

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Detalles Bibliográficos
Autores principales: Estades Ayuso, Virginia, Pickles, Sarah, Todd, Tiffany, Yue, Mei, Jansen-West, Karen, Song, Yuping, González Bejarano, Jesús, Rawlinson, Bailey, DeTure, Michael, Graff-Radford, Neill R., Boeve, Bradley F., Knopman, David S., Petersen, Ronald C., Dickson, Dennis W., Josephs, Keith A., Petrucelli, Leonard, Prudencio, Mercedes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441763/
https://www.ncbi.nlm.nih.gov/pubmed/37605276
http://dx.doi.org/10.1186/s13024-023-00646-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441763/
https://www.ncbi.nlm.nih.gov/pubmed/37605276
http://dx.doi.org/10.1186/s13024-023-00646-z

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