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Substrate topographies modulate the secretory activity of human bone marrow mesenchymal stem cells

BACKGROUND: Mesenchymal stem cells (MSCs) secrete a diversity of factors with broad therapeutic potential, yet current culture methods limit potency outcomes. In this study, we used topographical cues on polystyrene films to investigate their impact on the secretory profile and potency of bone marro...

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Detalles Bibliográficos
Autores principales: Rosado-Galindo, Heizel, Domenech, Maribella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441765/
https://www.ncbi.nlm.nih.gov/pubmed/37605275
http://dx.doi.org/10.1186/s13287-023-03450-0