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Time-Restricted Feeding and Intermittent Fasting as Preventive Therapeutics: A Systematic Review of the Literature

Multiple studies have shown that intermittent fasting (IF) is associated with better health conditions and longer lifespans, as is time-restricted feeding (TRF). One crucial explanation is that IF and TRF permit a set length of time for caloric ingestion, during which our systems activate a variety...

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Autores principales: Jaramillo, Arturo P, Castells, Javier, Ibrahimli, Sabina, Jaramillo, Luisa, Briones Andriuoli, Rebeca R, Moncada, Denisse, Revilla, Jhoanny C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441815/
https://www.ncbi.nlm.nih.gov/pubmed/37609101
http://dx.doi.org/10.7759/cureus.42300
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author Jaramillo, Arturo P
Castells, Javier
Ibrahimli, Sabina
Jaramillo, Luisa
Briones Andriuoli, Rebeca R
Moncada, Denisse
Revilla, Jhoanny C
author_facet Jaramillo, Arturo P
Castells, Javier
Ibrahimli, Sabina
Jaramillo, Luisa
Briones Andriuoli, Rebeca R
Moncada, Denisse
Revilla, Jhoanny C
author_sort Jaramillo, Arturo P
collection PubMed
description Multiple studies have shown that intermittent fasting (IF) is associated with better health conditions and longer lifespans, as is time-restricted feeding (TRF). One crucial explanation is that IF and TRF permit a set length of time for caloric ingestion, during which our systems activate a variety of mechanisms that lead to the enhancement and renewal of different body systems. Accordingly, the benefits of IF and TRF are a lot greater than those of complete calorie restriction (CR). Accordingly, TRF and IF offered the underpinnings for human studies that revealed that when we eat and when we are fasting, we experience fluctuations in all body systems. For relevant medical literature, we investigated medical databases such as PubMed/Medline, PubMed Central, Cochrane Library, and Google Scholar. The chosen articles were evaluated based on eligibility criteria and vetted by quality evaluation methods; 15 finished research papers were included in the study. Of the 15 recognized studies, four were systematic reviews of literature, and 11 were review articles. The chosen publications all examined the efficacy and comparability with other restrictive diets. The study articles indicated that the advantages of IF and TRF represent complex interplay involving periodic digestion of food, gut flora, and the circadian clock. Accordingly, further research is necessary to get a comprehensive grasp of this very complex molecular blueprint. This could aid in producing an effectively planned food treatment that can regulate numerous chronic health ailments and disorders. Furthermore, it might lead to the development and investigation of new pharmacological medicines that mimic the nutritional and therapeutic benefits of IF for those who are unwilling or unable to follow this kind of feeding regimen.
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spelling pubmed-104418152023-08-22 Time-Restricted Feeding and Intermittent Fasting as Preventive Therapeutics: A Systematic Review of the Literature Jaramillo, Arturo P Castells, Javier Ibrahimli, Sabina Jaramillo, Luisa Briones Andriuoli, Rebeca R Moncada, Denisse Revilla, Jhoanny C Cureus Internal Medicine Multiple studies have shown that intermittent fasting (IF) is associated with better health conditions and longer lifespans, as is time-restricted feeding (TRF). One crucial explanation is that IF and TRF permit a set length of time for caloric ingestion, during which our systems activate a variety of mechanisms that lead to the enhancement and renewal of different body systems. Accordingly, the benefits of IF and TRF are a lot greater than those of complete calorie restriction (CR). Accordingly, TRF and IF offered the underpinnings for human studies that revealed that when we eat and when we are fasting, we experience fluctuations in all body systems. For relevant medical literature, we investigated medical databases such as PubMed/Medline, PubMed Central, Cochrane Library, and Google Scholar. The chosen articles were evaluated based on eligibility criteria and vetted by quality evaluation methods; 15 finished research papers were included in the study. Of the 15 recognized studies, four were systematic reviews of literature, and 11 were review articles. The chosen publications all examined the efficacy and comparability with other restrictive diets. The study articles indicated that the advantages of IF and TRF represent complex interplay involving periodic digestion of food, gut flora, and the circadian clock. Accordingly, further research is necessary to get a comprehensive grasp of this very complex molecular blueprint. This could aid in producing an effectively planned food treatment that can regulate numerous chronic health ailments and disorders. Furthermore, it might lead to the development and investigation of new pharmacological medicines that mimic the nutritional and therapeutic benefits of IF for those who are unwilling or unable to follow this kind of feeding regimen. Cureus 2023-07-22 /pmc/articles/PMC10441815/ /pubmed/37609101 http://dx.doi.org/10.7759/cureus.42300 Text en Copyright © 2023, Jaramillo et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Jaramillo, Arturo P
Castells, Javier
Ibrahimli, Sabina
Jaramillo, Luisa
Briones Andriuoli, Rebeca R
Moncada, Denisse
Revilla, Jhoanny C
Time-Restricted Feeding and Intermittent Fasting as Preventive Therapeutics: A Systematic Review of the Literature
title Time-Restricted Feeding and Intermittent Fasting as Preventive Therapeutics: A Systematic Review of the Literature
title_full Time-Restricted Feeding and Intermittent Fasting as Preventive Therapeutics: A Systematic Review of the Literature
title_fullStr Time-Restricted Feeding and Intermittent Fasting as Preventive Therapeutics: A Systematic Review of the Literature
title_full_unstemmed Time-Restricted Feeding and Intermittent Fasting as Preventive Therapeutics: A Systematic Review of the Literature
title_short Time-Restricted Feeding and Intermittent Fasting as Preventive Therapeutics: A Systematic Review of the Literature
title_sort time-restricted feeding and intermittent fasting as preventive therapeutics: a systematic review of the literature
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441815/
https://www.ncbi.nlm.nih.gov/pubmed/37609101
http://dx.doi.org/10.7759/cureus.42300
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