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Minoxidil weakens newly synthesized collagen in fibrotic synoviocytes from osteoarthritis patients

PURPOSE: Synovial fibrosis (SFb) formation and turnover attributable to knee osteoarthritis (KOA) can impart painful stiffness and persist following arthroplasty. To supplement joint conditioning aimed at maximizing peri-operative function, we evaluated the antifibrotic effect of Minoxidil (MXD) on...

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Detalles Bibliográficos
Autores principales: Sarkovich, Stefan, Issa, Peter P., Longanecker, Andrew, Martin, Davis, Redondo, Kaitlyn, McTernan, Patrick, Simkin, Jennifer, Marrero, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441905/
https://www.ncbi.nlm.nih.gov/pubmed/37605092
http://dx.doi.org/10.1186/s40634-023-00650-8