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Delineating the role of single-nucleotide polymorphism of CYP19 gene on aromatase activity in South Indian women with polycystic ovary syndrome

BACKGROUND: Polycystic ovary syndrome is a common multifactorial endocrinopathy disorder affecting 5–15% of reproductive women worldwide. The CYP19 gene encodes key enzyme aromatase involved in androgen-to-estrogen conversion which plays a crucial role in the pathophysiology of the syndrome. Very fe...

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Detalles Bibliográficos
Autores principales: Hegde, Pravesh, Shetty, Shilpa S., Shetty, Prasanna Kumar, Manjeera, Lakshmi, Shetty, D. Prashanth, Kumari, Suchetha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441965/
https://www.ncbi.nlm.nih.gov/pubmed/37603197
http://dx.doi.org/10.1186/s43141-023-00540-7