Acetylation increases expression, interaction with TRAPPC4 and surface localization of PD-L1

PD-L1 is an immune checkpoint inhibitor, whose surface expression may be exploited by cancer cells to escape T cell-mediated immune recognition. PD-L1 expression and nuclear localization can be affected by epigenetic modifications, such as acetylation. In this study, we showed that VPA, a class I/II...

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Detalles Bibliográficos
Autores principales: Romeo, Maria Anele, Gilardini Montani, Maria Saveria, Santarelli, Roberta, Benedetti, Rossella, Arena, Andrea, Cirone, Mara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442048/
https://www.ncbi.nlm.nih.gov/pubmed/37603071
http://dx.doi.org/10.1007/s12672-023-00766-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442048/
https://www.ncbi.nlm.nih.gov/pubmed/37603071
http://dx.doi.org/10.1007/s12672-023-00766-4

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