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Combining molecular dynamics simulations and scoring method to computationally model ubiquitylated linker histones in chromatosomes
The chromatin in eukaryotic cells plays a fundamental role in all processes during a cell’s life cycle. This nucleoprotein is normally tightly packed but needs to be unpacked for expression and division. The linker histones are critical for such packaging processes and while most experimental and si...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442151/ https://www.ncbi.nlm.nih.gov/pubmed/37527265 http://dx.doi.org/10.1371/journal.pcbi.1010531 |