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Combining molecular dynamics simulations and scoring method to computationally model ubiquitylated linker histones in chromatosomes

The chromatin in eukaryotic cells plays a fundamental role in all processes during a cell’s life cycle. This nucleoprotein is normally tightly packed but needs to be unpacked for expression and division. The linker histones are critical for such packaging processes and while most experimental and si...

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Detalles Bibliográficos
Autores principales: Sawade, Kevin, Marx, Andreas, Peter, Christine, Kukharenko, Oleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10442151/
https://www.ncbi.nlm.nih.gov/pubmed/37527265
http://dx.doi.org/10.1371/journal.pcbi.1010531

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